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| PharmaBlock Sciences (Nanjing), Inc. +86 400 025 5188 sales_china@pharmablock.com
PharmaBlock (USA), Inc. +1 408 735 7571/408 921 9969 salesusa@pharmablock.com |
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| “Aliphatic cyclic amino acids are fundamental building blocks of modern medicinal chemistry. The combination of readily functionalized amine and carboxyl groups attached to a chiral central core along with one or two potentially diverse side chains provides a unique three-dimensional structure with a high degree of functionality. This makes them invaluable as starting materials for syntheses of complex molecules, highly diverse elements for SAR campaigns, integral components of peptidomimetic drugs, and potential drugs on their own”.
(Reference: Mark A. T. Blaskovich J. Med. Chem. 2016, 59, 10807−10836) For example, the following 6 drugs which are under active clinical development or marketed, consist of different units of aliphatic cyclic amino acids. |
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